Breakthrough Natural Biological Fermentation: Salecan® Next-Generation High-Performance beta-Glucan

Amidst the global trends of sensitive skin repair and skin barrier care, Salecan® beta-glucan—a revolutionary ingredient derived from marine microorganisms—is leading the beauty industry into a new era of "high efficacy, high safety, and sustainability." As the world’s first natural, water-soluble beta-glucan obtained through biological fermentation, Salecan® distinguishes itself from traditional plant-derived beta-glucans extracted from cell walls. Its unique linear structure and exceptional biological activity provide superior repair capabilities and a luxurious sensory experience for personal care products.
 

Basic Information

• Product Name: Salecan® beta-Glucan

• INCI Name: Beta-Glucan

• CAS Code: 1439905-58-4

• Main Functions: Skin barrier repair, anti-inflammatory and soothing, deep moisturization, skin microbiota regulation, and sun protection assistance.

• Applicable Products: Serums, lotions, creams, masks, toners, as well as oral and hair care products.

Core Technical Advantages

1. Exclusive Marine Microbial Fermentation for a Pure, Natural Structure Unlike traditional β-glucans extracted from yeast or oat cell walls, Salecan® is derived from the extracellular polysaccharides secreted by the marine microorganism Rhizobium pusense ZX09. Produced through a gentle biological fermentation process and utilizing non-carboxymethylation technology, Salecan® ensures the integrity of its original linear structure. This maintains the bioactivity required for immune regulation while achieving 100% natural, transparent, and water-soluble advantages.

2. Clinically Proven Anti-Inflammatory and Repair Efficacy In LPS-induced inflammation models and fibroblast proliferation experiments, Salecan® has demonstrated potent repair efficacy:

• Significant Anti-inflammatory Effects: It effectively inhibits inflammatory factors such as IL-6 and TNF-α, helping to soothe sensitive skin and enhance the skin's defense system.

• Promotion of Collagen Synthesis: It significantly promotes Type I collagen secretion and continuously accelerates fibroblast proliferation within 24–72 hours, aiding in the reconstruction of damaged barriers for firmer, more elastic skin.
  
  

3. Superior Sensory and Physical Properties Salecan® offers unique viscosity properties. Compared to common yeast, oat, or mushroom-derived β-glucans, its aqueous solution provides excellent clarity and a refreshing, smooth skin feel. This makes it an ideal ingredient for premium skincare, offering both improved skin texture and long-lasting, refreshing hydration.

Why Choose Salecan®?

As more than just a moisturizer, Salecan® is a scientifically validated repair factor:

• 100% Water Soluble: It eliminates the formulation challenges associated with water-insoluble β-glucans, providing products with exceptional clarity and texture.

• Unique Linear Structure: By preserving the original linear structure without carboxymethylation, it ensures both safety and high ingredient activity.

• Comprehensive Applications: Suitable for various systems including serums, lotions, and creams.

Rigorous Cellular Research Supporting Efficacy

We have conducted extensive cellular studies demonstrating Salecan®’s efficacy in soothing, moisturizing, and repairing the skin:

1. Deep Moisturizing and Barrier Repair In 3D human epidermal model studies, Salecan® significantly enhanced the expression of key moisture-regulating proteins:

• Hyaluronic Acid (HA) secretion increased by 150.00%

• Filaggrin (FLG) expression increased by 100.00%

• Aquaporin-3 (AQP3) expression increased by 111.11%
  
  

2. A "Soothing Shield" for Sensitive Skin Salecan® provides effective inhibition against common sensitive skin triggers:

• HMGB1 Inhibition: In inflammation models, Salecan® significantly reduced the levels of HMGB1 (an inflammatory marker), alleviating inflammatory responses.
  
  

• Pain Relief: In TRPV1 (the receptor for pain and heat sensation) over-activation tests, Salecan® demonstrated a 37.11% inhibition rate, effectively reducing discomfort caused by external stimuli.